20 Fast SEC EDGAR, FDA Biotech & US B2B Lead Generation JSON APIs for Python, Clay, n8n & MCP AI Agents

Parsing raw US government regulatory filings, XBRL financial statements, FDA clearances, and healthcare registries is notoriously difficult due to XSLT stylesheet wrappers, changing US-GAAP accounting tags, and deeply nested XML tables.

To solve this for quantitative developers, B2B growth teams, and AI agent builders, I built and published a complete 20-API Financial, Biotech, and B2B Lead Intelligence Suite on Apify (Mehdad DataLabs).

Every API in this suite runs on pure asynchronous Python httpx (zero headless browser overhead, executing in 3 to 6 seconds on 256 MB RAM), outputs flat, structured JSON, CSV, or Excel tables, and works natively as an MCP (Model Context Protocol) server for Claude Desktop, Cursor, Clay, Make, and n8n workflows.

Here is the complete 20-API directory organized by category:

PART 1: WALL STREET & SEC EDGAR INTELLIGENCE APIS (10 APIS)

1. SEC Form 4 Insider Trading Scraper & XML Parser API
   Strips SEC XSLT wrappers and parses raw Form 4 XML filings to extract exact CEO, CFO, Director, and 10% Owner open-market stock purchases (Code P) and sales (Code S), share counts, prices, and total dollar values:
   https://apify.com/mehdad-datalabs/sec-form-4-insider-trading-scraper-xml-parser-api

2. SEC Form 13F Institutional Holdings & Hedge Fund Whale Scraper
   Parses quarterly Form 13F-HR XML information tables for Berkshire Hathaway (Warren Buffett), Scion Asset Management (Michael Burry), BlackRock, Citadel, and Renaissance Technologies—with automatic portfolio weight (%) calculation and Put/Call option detection:
   https://apify.com/mehdad-datalabs/sec-13f-institutional-holdings-hedge-fund-whale-scraper

3. SEC Form N-PORT Mutual Fund & ETF Portfolio Holdings API
   Extracts monthly and quarterly Form N-PORT-P XML portfolio holdings for Vanguard, BlackRock iShares, Fidelity, and SPDR ETFs and mutual funds, including equities, bonds, CUSIPs, ISINs, USD market values, and net asset weights (%):
   https://apify.com/mehdad-datalabs/sec-nport-etf-mutual-fund-holdings-xml-scraper

4. SEC 10-K & 10-Q XBRL Financial Statements & Earnings API
   Normalizes audited US-GAAP XBRL CompanyFacts data into clean quarterly (10-Q) and annual (10-K) financial statement rows—including Revenue, Net Income, Net Profit Margin (%), Diluted EPS, Operating Cash Flow, R&D Spend, Cash, Total Assets, Liabilities, and Equity:
   https://apify.com/mehdad-datalabs/sec-10k-10q-xbrl-financial-statements-earnings-api

5. SEC Form 8-K Corporate Events, M&A & Executive Change Scraper
   Automatically decodes cryptic SEC Form 8-K item codes into plain-English catalysts—including Item 5.02 (CEO/CFO/Director appointments and departures), Item 2.02 (Earnings releases), Item 1.01/2.01 (M&A deals), Item 2.05 (Layoffs), and Item 1.05 (Cybersecurity breaches):
   https://apify.com/mehdad-datalabs/sec-8k-corporate-events-ma-executive-change-scraper

6. SEC Schedule 13D & 13G Activist Investor & 5%+ Ownership API
   Tracks real-time Schedule 13D (active/hostile takeover campaigns and board seat demands) and Schedule 13G (passive 5%+ institutional whale block stakes) plus 13D/A amendments:
   https://apify.com/mehdad-datalabs/sec-schedule-13d-13g-activist-investor-ownership-api

7. SEC Form S-1 IPO Pipeline & Form 144 Insider Sale Notice API
   Monitors Rule 144 proposed restricted stock sales by founders and VCs (Form 144), initial public offering registrations (Form S-1 and F-1), secondary shelf dilution offerings (Form S-3 and 424B5), and SEC Notices of Effectiveness (EFFECT):
   https://apify.com/mehdad-datalabs/sec-ipo-s1-form144-insider-sale-scraper

8. SEC DEF 14A Executive Compensation & Proxy Statement API
   Extracts Definitive Annual Proxy Statements (DEF 14A), Merger Proxies (DEFM14A), Activist Proxy Contests (DFAN14A), and Investor Presentation Decks (DEFA14A) covering CEO compensation tables, golden parachutes, and shareholder votes:
   https://apify.com/mehdad-datalabs/sec-def14a-ceo-executive-compensation-proxy-scraper

9. SEC Form 20-F & 6-K Global ADR & Foreign Stock Filings API
   Purpose-built for non-US companies and ADRs traded on NYSE and Nasdaq (such as TSMC, ASML, Novo Nordisk, Alibaba, AstraZeneca, and SAP) that file audited annual reports on Form 20-F/40-F and monthly revenue or earnings releases on Form 6-K:
   https://apify.com/mehdad-datalabs/sec-20f-6k-foreign-adr-international-stock-scraper

10. SEC Form D Startup Funding, VC Raise & Founder B2B Lead API
    Parses raw SEC Form D XML filings submitted by private startups within 15 days of raising Venture Capital or Seed funding—extracting Startup Name, Exact Dollar Amount Raised ($), Founder/CEO/Director Full Names and Roles, Direct Company Phone Number, and HQ Address:
    https://apify.com/mehdad-datalabs/sec-form-d-startup-funding-vc-b2b-lead-scraper

PART 2: BIOTECH, PHARMA, MEDTECH & FDA CATALYST APIS (4 APIS)

1. FDA Drug Approvals, NDA/BLA Biotech Catalyst & Pharma API
   Extracts official US FDA (Drugs@FDA / openFDA) New Drug Applications (NDA), Biologics License Applications (BLA), and Generic Approvals (ANDA), including Priority Review status, active ingredients, and pharma sponsor companies:
   https://apify.com/mehdad-datalabs/fda-drug-approvals-biotech-catalyst-pharma-b2b-scraper

2. ClinicalTrials.gov Phase 1-3 Biotech Catalyst & B2B Lead API
   Extracts active and completed clinical studies from ClinicalTrials.gov REST API v2—capturing NCT ID, Trial Phase (Phase 1, 2, 3), Lead Pharma Sponsor, Primary Completion Date (biotech readout catalyst date), Drug Interventions, and Central Study Contact Emails and Phone Numbers:
   https://apify.com/mehdad-datalabs/clinical-trials-biotech-catalyst-cro-b2b-lead-scraper

3. FDA 510(k) Medical Device Clearances & MedTech B2B Lead API
   Extracts official US FDA 510(k) premarket medical device clearances—including the MedTech Applicant Company Name, Direct Contact Person Name, HQ Street Address, Cleared Device Trade Name, Medical Specialty, and Decision Date:
   https://apify.com/mehdad-datalabs/fda-510k-medical-device-clearances-medtech-b2b-scraper

4. FDA Drug, Device & Food Recall Enforcement & Legal Lead API
   Extracts Class I (life-threatening), Class II, and Class III FDA product recalls across Pharmaceuticals (DRUG), Medical Devices (DEVICE), and Food (FOOD)—capturing Recalling Firm Names, Recall Reasons, Product Quantities, and Nationwide Distribution Patterns for mass-tort law firms and compliance teams:
   https://apify.com/mehdad-datalabs/fda-product-recalls-safety-enforcement-b2b-scraper

PART 3: B2B LEAD GENERATION, GOVCON & BANKING APIS (6 APIS)

1. US Federal Government Contract Awards & DoD B2B Lead Scraper
   Extracts US Federal Government and Pentagon (DoD) contract awards by keyword (Artificial Intelligence, Cybersecurity, Cloud, Defense) or recipient company name, sorted by largest dollar contract value:
   https://apify.com/mehdad-datalabs/us-federal-government-contract-awards-dod-b2b-scraper

2. US Doctor, Dentist & Medical Clinic B2B Lead Scraper API
   Extracts verified US physicians, dentists, surgeons, med-spas, and medical clinics from the CMS NPPES NPI Registry—including Clinic Owner / Authorized Official Name, Title, Direct Phone Number, Practice Address, Specialty Taxonomy, and State License Number:
   https://apify.com/mehdad-datalabs/us-doctor-dentist-clinic-healthcare-b2b-lead-scraper

3. US Pharmacy, Clinical Lab & Medical Supply B2B Lead API
   Strictly targets NPI-2 commercial healthcare organizations to extract Independent Pharmacies, Compounding Pharmacies, Clinical Diagnostic Laboratories, and DME Medical Suppliers with Verified Owner/Director Names, Direct Phone Numbers, DBA Names, and Licenses:
   https://apify.com/mehdad-datalabs/us-pharmacy-medical-lab-dme-b2b-lead-scraper

4. FDIC US Bank Directory, Deposits, Assets & B2B Lead API
   Extracts official FDIC BankFind directory and quarterly Call Report financial health data for active US commercial, regional, and community banks—including Total Assets ($), Total Deposits ($), Net Income, ROA %, ROE %, Branch Count, Website URL, and HQ Address:
   https://apify.com/mehdad-datalabs/fdic-us-bank-directory-deposits-assets-b2b-scraper

5. CFPB Fintech & Bank Consumer Complaint Intelligence API
   Extracts consumer financial complaints and regulatory dispute disclosures against banks, fintech apps, crypto exchanges (Coinbase, Robinhood, PayPal, Zelle), and lenders—ideal for fintech compliance benchmarking, equity risk research, and consumer protection law firms:
   https://apify.com/mehdad-datalabs/cfpb-fintech-bank-consumer-complaint-b2b-scraper

6. US Public Company B2B Directory, SIC & HQ Phone API
   Enriches any list of US stock tickers (Nasdaq and NYSE) with official SEC corporate entity data—including Verified Corporate HQ Switchboard Phone Number, Physical Street Address, 9-Digit IRS EIN Tax ID, 4-Digit SIC Industry Code, and Filer Size Tier for Clay and CRM workflows:
   https://apify.com/mehdad-datalabs/us-public-company-b2b-profile-sic-hq-phone-scraper

HOW TO USE THESE APIS IN PYTHON, N8N, CLAY OR CLAUDE MCP

All 20 Actors can be tested for free using Apify's free monthly credit tier and called via:

• REST API (GET/POST JSON endpoints for Clay, Make, Zapier, or custom webhooks)
• Official Apify Node inside n8n for automated daily pipelines
• Python and Node.js SDKs (apify-client)
• Model Context Protocol (MCP) for giving Claude Desktop and Cursor live access to SEC, FDA, and B2B datasets

You can view the full portfolio here:
https://apify.com/mehdad-datalabs

If you need a custom field added to any of these parsers or have a request for a new financial or B2B dataset, feel free to drop a comment below!